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Product Specifications

Item Specification Product Name Chromium Picolinate Alias Chromium(III) Pyridine-2-carboxylate, Chromium Tripicolinate, Picolinic Acid Chromium(III) Salt CAS Number 14639-25-9 Molecular Formula C₁₈H₁₂CrN₃O₆ Molecular Weight 418.30 Appearance Violet to reddish free-flowing crystalline powder, odorless Assay ≥99% Test Method HPLC / Titration / Atomic Absorption Spectroscopy Shelf Life 24 Months Storage Condition Store in a cool, dry, well-ventilated place, away from heat, sparks and oxidizing agents

Why Is Chromium Picolinate So Widely Recognized?

The widespread adoption of Chromium Picolinate is closely tied to growing public awareness of the critical physiological role of trivalent chromium, an essential trace mineral that participates in hundreds of key biological processes across the human body. Trivalent chromium is a core active component of the Glucose Tolerance Factor (GTF) found in brewer's yeast, which plays a fundamental role in glucose metabolism, lipid regulation and endocrine balance.

As a highly bioavailable chelated form of trivalent chromium, Chromium Picolinate delivers far higher absorption efficiency than common inorganic chromium sources. It was first synthesized and identified as a high-performance chromium supplement in 1977, and completed full safety assessment in the United States to be approved for use as a food supplement ingredient in 2005, after which it gained extensive research and application in the fields of nutrition science, sports medicine and functional food development, establishing its position as a staple ingredient in modern metabolic wellness formulations.

Key Benefits of Chromium Picolinate

• Supports Steady Cellular Energy Metabolism‌

As an essential constituent of the Glucose Tolerance Factor, Chromium Picolinate enhances insulin efficiency to help the body convert nutrients into ATP, the primary usable energy source for cells. It supports efficient cellular energy turnover, reducing energy fluctuations that lead to fatigue to maintain consistent daily vitality.

• Promotes Balanced Blood Glucose Levels for Metabolic Wellness‌

Chromium Picolinate exerts bidirectional regulatory effects on blood glucose, helping to lower hyperglycemia in patients with abnormal glucose tolerance while also alleviating adverse hypoglycemic responses. Supplementing 200-1000μg of Chromium Picolinate daily has been clinically proven to effectively improve glycemic control in type 2 diabetes patients, and also helps reduce serum triglyceride and total cholesterol levels to support long-term cardiovascular and metabolic health.

• Optimizes Body Composition for Active Lifestyle Support‌

Widely incorporated into sports nutrition formulations, Chromium Picolinate enhances muscle protein synthesis while supporting healthy fat breakdown. It helps active adults increase lean muscle mass, reduce excess body fat accumulation, and improve exercise recovery efficiency to boost daily performance and fitness outcomes.

• Enhances Anti-Stress Ability and Endocrine Stability‌

Chromium Picolinate helps regulate endocrine function, reducing the physiological burden caused by chronic environmental and mental stress. It supports users with high-stress lifestyles to maintain stable physical state and avoid metabolic disturbances induced by prolonged stress exposure.

• Delivers Reliable Antioxidant and Immune Modulation Effects‌

As a p38 MAPK activator with confirmed antioxidant activity, Chromium Picolinate mitigates oxidative stress damage induced by abnormal glucose metabolism, and helps regulate immune function to reduce health risks linked to long-term trace mineral deficiency.

Wide Range of Industry Applications

Chromium Picolinate is adopted across multiple product categories globally, including:

• Blood glucose management targeted dietary supplements
• Sports nutrition and weight management functional products
• Daily metabolic maintenance health formulations
• Livestock and poultry feed additives for animal nutrition
• Multi-vitamin and trace mineral complex daily wellness products

Common applicable dosage forms cover capsules, tablets, vegetarian tablets, powder blends, solid drink premixes and standardized feed additive formulations.

Chromium Picolinate vs Other Popular Metabolic Wellness Ingredients

As the metabolic health market continues to expand, Chromium Picolinate maintains its irreplaceable position as a science-backed staple ingredient:

Ingredient Primary Function Chromium Picolinate High-bioavailability trivalent chromium source, enhances insulin sensitivity, regulates glucose and lipid metabolism, optimizes body composition Alpha Lipoic Acid Universal antioxidant that assists in improving insulin responsiveness, reduces oxidative stress White Kidney Bean Extract Natural amylase inhibitor that partially blocks carbohydrate absorption to support weight management L-Carnitine L-Tartrate Facilitates fatty acid transport for mitochondrial oxidation to enhance fat utilization during exercise Chromium Yeast Natural source of organic chromium with moderate absorption efficiency derived from brewer's yeast

Numerous leading brands combine Chromium Picolinate with these complementary functional ingredients to create synergistic, all-round metabolic support formulations.

Promising Global Market Opportunity

The global metabolic health and weight management market is maintaining strong growth momentum as consumers increasingly prioritize preventive healthcare strategies and proactive chronic disease risk management. Multiple key trends are driving continuously rising market demand for Chromium Picolinate:

• Surging public awareness of trace mineral health benefits
• Rapid expansion of the global pre-diabetes and metabolic dysfunction population
• Continuous booming of premium sports nutrition and active lifestyle supplement categories
• Growing consumer preference for ingredients supported by rigorous scientific evidence and clinical data
• Increasing regulatory approval of safe and effective functional feed additives in livestock farming

As a result, Chromium Picolinate remains one of the most commercially attractive core ingredients for brands developing next-generation wellness products across human nutrition and animal health sectors.

Frequently Asked Questions

1.What is Chromium Picolinate?‌

Chromium Picolinate is an orally active chelated coordination complex formed by trivalent chromium (Cr³⁺) bound with three picolinic acid molecules. It is a high-efficiency supplementary source of the essential trace mineral chromium that supports normal physiological glucose and lipid metabolism in the human body.

2.What is the safety profile of Chromium Picolinate?‌

Trivalent chromium is an essential nutrient for human health, and Chromium Picolinate demonstrates excellent safety when used within the recommended dosage range. The WHO International Agency for Research on Cancer has classified Chromium(III) compounds in Group 3 carcinogen list, which means there is insufficient evidence to confirm their carcinogenic risk to humans under normal consumption scenarios. The safe daily intake range for adults is 50-200μg, with the maximum tolerable daily intake set at 1000μg. The oral LD₅₀ of Chromium Picolinate in rats is greater than 2000mg/kg, with no confirmed mutagenic or genotoxic effects.

3.What is the difference between Chromium Picolinate and other chromium supplements?‌

Compared to inorganic chromium sources such as chromium chloride, Chromium Picolinate has a significantly higher intestinal absorption rate (1-3%) and far better biological activity. Compared to natural chromium sources like chromium yeast, it offers higher purity, precise content consistency and easier formulation standardization for industrial production.

4.Can Chromium Picolinate be used in animal feed applications?‌

Yes. As an approved trace mineral feed additive, Chromium Picolinate can improve livestock and poultry growth performance, increase lean meat percentage, enhance animal anti-stress and reproductive capacity, and effectively improve feed conversion rate to bring tangible economic benefits to modern farming operations.

5.What purity level is typically available for commercial use?‌
Premium-grade Chromium Picolinate for dietary supplement and functional food applications is commonly produced at purity levels of 99% or higher, with full compliance with USP reference standards and global regulatory requirements.

Looking for a Reliable Chromium Picolinate Supplier?

As demand for evidence-based metabolic wellness products continues to grow, ingredient quality consistency, traceability and steady supply chain reliability have become top priorities for supplement manufacturers and animal nutrition producers. Nutrient Trail supplies high-purity Chromium Picolinate designed for dietary supplement, functional food, beverage and livestock feed additive applications.Comprehensive technical documentation including product specifications, Certificate of Analysis (COA), MSDS and full regulatory compliance information is available to fully support your product development and commercialization process.